Spark PLUS UV395™ anti-mouse CD11c Antibody, CD11c, N418,BioLegend,117377

Additional reported applications (for the relevant formats) include: immunoprecipitation3, immunohistochemical staining of acetone-fixed frozen sections3, immunofluorescence microscopy5, 9(Alexa Fluor® 488 conjugated N418 was used for IHC in frozen sections10), and spatial biology (IBEX)22,23.

Host

Armenian Hamster

Reactivity

Mouse

Application

FC - Quality tested

Platform ID

BAB259087516

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameSpark PLUS UV395™ anti-mouse CD11c Antibody, CD11c, N418
Cat. No.117377
HostArmenian Hamster
RRIDAB_3106240 (BioLegend Cat. No. 117377)AB_3106240 (BioLegend Cat. No. 117378)
IsotypeArmenian Hamster IgG
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberN418
Concentration0.2 mg/mL
TargetCD11c
ImmunogenMouse spleen dendritic cells
PurityThe antibody was purified by affinity chromatography and conjugated with Spark PLUS UV395™ under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD11c is a 150 kD glycoprotein also known as αXintegrin, CR4, and p150. CD11c forms a αXβ2heterodimer with β2integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

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