Spark Red™ 718 anti-human CD11c (Flexi-Fluor™) Antibody, CD11c, S-HCL-3,BioLegend,285112

Additional reported applications (for the relevant formats) include: immunohistochemistry on frozen tissue sections1,2,3,4and immunoprecipitation1.

Host

Mouse

Reactivity

Human

Application

FC

Platform ID

BAB588485651

BioLegend

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Product Specifications
Scientific Background

Specifications

NameSpark Red™ 718 anti-human CD11c (Flexi-Fluor™) Antibody, CD11c, S-HCL-3
Cat. No.285112
HostMouse
RRIDAB_3106364 (BioLegend Cat. No. 285112)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC
ClonalityMonoclonal
Clone NumberS-HCL-3
Concentration0.2 mg/mL
TargetCD11c
ImmunogenSpleen cells from patient diagnosed with hairy cell leukemia.
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Red™ 718 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αxand CR4. CD11c non-covalently associates with integrin β2(CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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