Spark Red™ 718 anti-human TCR Cβ1 Antibody, TCR Cβ1, JOVI.1,BioLegend,383521
Clone JOVI.1 can interfere with the binding of clone IP26 on target cells.
Host
Mouse
Reactivity
Human
Application
FC - Quality tested
Platform ID
BAB928489957
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameSpark Red™ 718 anti-human TCR Cβ1 Antibody, TCR Cβ1, JOVI.1
Cat. No.383521
HostMouse
RRIDAB_3716916 (BioLegend Cat. No. 383521)AB_3716916 (BioLegend Cat. No. 383522)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberJOVI.1
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetTCR Cbeta1
ImmunogenTransgenic mouse lymphocytes expressing human Vβ3-Cβ1 TCR
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Red™ 718 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The T cell receptor beta chain constant region-1 (TCR Cβ1), also known as TRBC1, is a segment of the TCR beta chain that forms the constant region of the T cell receptor. The rearrangement of TCR genes during T cell development leads to the selection of one of two TCR beta constant regions – C1 or C2. Detection of TRBC1 within a comprehensive T cell panel can be used as evidence of clonality akin to the use of kappa/lambda light chain detection in the diagnosis of plasma cell malignancies.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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