Spark Red™ 718 anti-mouse CD185 (CXCR5) Antibody, CD185, L138D7,BioLegend,145543
Clone L138D7 staining works optimally at room temperature or 4°C. Unlike other chemokine receptor antibodies, avoid using L138D7 at 37°C.
Host
Rat
Reactivity
Mouse
Application
FC - Quality tested
Platform ID
BAB308563756
BioLegend
Contact
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Product Specifications
Scientific Background
Specifications
NameSpark Red™ 718 anti-mouse CD185 (CXCR5) Antibody, CD185, L138D7
Cat. No.145543
HostRat
RRIDAB_3097525 (BioLegend Cat. No. 145543)AB_3097525 (BioLegend Cat. No. 145544)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberL138D7
Concentration0.5 mg/mL
TargetCD185
ImmunogenmCXCR5-transfected cells
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Red™ 718 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD185 is also known as CXCR5. It is the receptor for chemokine CXCL13/BLC, which is chemotactic for B cells. CXCR5 is expressed on B cells and a subset of T cells in the spleen, neuronal tissue, lymph nodes, and bone marrow. It is important for migration of B cells into the B cell follicles of the spleen and Peyer’s patches. Follicular helper T cells (Tfh) also express CXCR5 and the ability of these cells to migrate to the lymph node is modulated by the balanced expression of CCR7 and CXCR5.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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