Spark Red™ 718 anti-mouse CD192 (CCR2) (Flexi-Fluor™) Antibody, CD192, SA203G11,BioLegend,285110

Host

Rat

Reactivity

Mouse

Application

FC

Platform ID

BAB200792982

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameSpark Red™ 718 anti-mouse CD192 (CCR2) (Flexi-Fluor™) Antibody, CD192, SA203G11
Cat. No.285110
HostRat
RRIDAB_3106362 (BioLegend Cat. No. 285110)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationFC
ClonalityMonoclonal
Clone NumberSA203G11
Concentration0.2 mg/mL
TargetCD192
ImmunogenMouse CCR2 transfectants.
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Red™ 718 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD192, also known as CCR2, is a 42 kD G-protein coupled receptor that is associated with bone marrow homeostasis. Specifically, CD192 mediates monocyte chemotaxis and acts as a receptor for monocyte chemoattractant protein 1 (MCP-1). CD192 is primarily expressed on monocytes and macrophages, with some expression on basophils. It is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis and cancer.

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