Spark Red™ 718 anti-rat CD11b/c (Flexi-Fluor™) Antibody, CD11b/c, OX-42,BioLegend,285346
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections1,2, immunoprecipitation3,in vivoandin vitroblocking of C3bi binding3,4.
Host
Mouse
Reactivity
Rat
Application
FC
Platform ID
BAB950479397
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameSpark Red™ 718 anti-rat CD11b/c (Flexi-Fluor™) Antibody, CD11b/c, OX-42
Cat. No.285346
HostMouse
RRIDAB_3683276 (BioLegend Cat. No. 285346)
IsotypeMouse IgG2a, κ
ReactivityRat
ApplicationFC
ClonalityMonoclonal
Clone NumberOX-42
Concentration0.2 mg/mL
TargetCD11b or CD11c
ImmunogenRat peritoneal macrophages.
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Red™ 718 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
The OX-42 antibody reacts with the CR3 complement (C3bi) receptor expressed on monocytes, granulocytes, macrophages, dendritic cells, and NK cells. This antibody appears to recognize a common epitope shared between CD11b and CD11c (integrin αMand αXchains). The OX-42 antibody precipitates three polypeptides with apparent molecular weights of 160, 103, and 95 kD, respectively. This antibody has been shown to block the formation of complement-mediated rosettes and leukocyte migration.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.