Spark Violet™ 500 anti-human CD32 Antibody, CD32, FUN-2,BioLegend,303234

Additional reported applications (for the relevant formats) include: immunohistochemical staining3of acetone-fixed frozen tissue sections.Clone FUN-2 recognizes both CD32A and CD32B.

Host

Mouse

Reactivity

Human

Application

FC - Quality tested

Platform ID

BAB286185767

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

BioLegend

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameSpark Violet™ 500 anti-human CD32 Antibody, CD32, FUN-2
Cat. No.303234
HostMouse
RRIDAB_2936547 (BioLegend Cat. No. 303233)AB_2936547 (BioLegend Cat. No. 303234)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationFC - Quality tested
ClonalityMonoclonal
Clone NumberFUN-2
ConcentrationLot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysisonline tool.)
TargetCD32
PurityThe antibody was purified by affinity chromatography and conjugated with Spark Violet™ 500 under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
StorageThe antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.