Src antibody,Genetex,GTX27950

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IP

Conjugate

Unconjugated

Platform ID

BAB495564068

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameSrc antibody
Cat. No.GTX27950
Gene ID (Entrez)6714
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IP
ClonalityPolyclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSRC
ImmunogenPeptide mapping to the amino terminus of human c-Src p60.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 0.2% Gelatin,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

SRC proto-oncogene, non-receptor tyrosine kinase , ASV , SRC1 , THC6 , c-SRC , p60-Src

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