Src (phospho Tyr530) antibody,Genetex,GTX78941

Host

Rabbit

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB493542510

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSrc (phospho Tyr530) antibody
Cat. No.GTX78941
Gene ID (Entrez)6714
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetSRC
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Src around the phosphorylation site of tyrosine 529 (P-Q-Y(p) -Q-P). The Tyr529 of human Src is equivalent to Tyr527 of chicken Src.
PurityPurified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.From serum
Appearance/FormLiquid
FormulationPBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format),0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

ASV,SRC,SRC protooncogene, nonreceptor tyrosine kinase,SRC1,THC6,cSRC,p60Src,c Src,SRC proto-oncogene, non-receptor tyrosine kinase

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