Stat3 Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-52235r-bf680-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, IF

Conjugate

AbBy Fluor-680

Platform ID

BAB148860220

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameStat3 Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-52235r-bf680-100ul
Accession NumberP40763
Gene ID (Entrez)6774
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationAbBy Fluor-680
ApplicationWB, IF
Working DilutionsWB:1:300-5000 | IF:
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

Synonyms

APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3

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