Surfeit Locus Protein 4 Antibody (YA2465),MedChemexpress,HY-P82720

Surfeit Locus Protein 4 Antibody (YA2465) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Surfeit Locus Protein 4.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,ICC/IF

Conjugate

Non-conjugated

Platform ID

BAB077967370

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

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Product Specifications
Scientific Background
Synonyms

Specifications

NameSurfeit Locus Protein 4 Antibody (YA2465)
Cat. No.HY-P82720
Accession NumberO15260
Gene ID (Entrez)6836
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,ICC/IF
Working DilutionsWB: 1:500-1:1000; ICC/IF: 1:50-1:200
ClonalityRecombinant,Monoclonal
Clone NumberYA2465
Molecular WeightPredicted band size: 30 kDa; Observed band size: 30 kDa
ImmunogenA synthetic peptide of human SURF4 aa:144-157.
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Surfeit Locus Protein 4 is an endoplasmic reticulum cargo receptor that facilitates lipoprotein export by recruiting cargos into COPII vesicles for secretion. It acts as a cargo receptor for lipoproteins bearing APOB and APOA1, regulating lipoprotein delivery and lipid homeostasis maintenance. It synergizes with the GTPase SAR1B to mediate the transport of circulating lipoproteins and promotes the secretion of PCSK9 and erythropoietin (EPO). It may also play a role in maintaining the architecture of the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) and the Golgi. by similar: Cooperates with GTPase SAR1B for lipoprotein transport; enhances secretion of PCSK9 and EPO; potentially involved in ERGIC and Golgi structure maintenance.

Synonyms

ERV29

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