Synapsin-1 (D12G5) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate)#11127,Cell Signaling Technology (CST),11127

Synapsin-1 (D12G5) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate) detects endogenous levels of total synapsin protein. The antigen is 100% conserved between human synapsin-1a and synapsin-1b.

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

Immunofluorescence (Frozen): 1:50

Platform ID

BAB269148891

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSynapsin-1 (D12G5) Rabbit Monoclonal Antibody (Alexa Fluor®647 Conjugate)#11127
Cat. No.11127
Accession NumberP17600
Gene ID (Entrez)17600, 6853
HostRabbit
SensitivityEndogenous
ReactivityHuman, Mouse, Rat
ApplicationImmunofluorescence (Frozen): 1:50
ImmunogenIgG
FormulationSupplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
StorageSupplied in PBS (pH 7.2), less than 0.1% sodium azide and 2 mg/ml BSA. Store at 4°C. Do not aliquot the antibody. Protect from light. Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Synapsins, a group of at least five related members (synapsins Ia, Ib, IIa, IIb, and IIIa), are abundant brain proteins essential for regulating neurotransmitter release (1,2). All synapsins contain a short amino-terminal domain that is highly conserved and phosphorylated by PKA or CaM kinase I (1). Phosphorylation of the synapsin amino-terminal domain at Ser9 inhibits its binding to phospholipids and dissociates synapsins from synaptic vesicles (2).Greengard, P. (1987)Mol Neurobiol1, 81-119.Hosaka, M. et al. (1999)Neuron24, 377-87.Alternate NamesBrain protein 4.1; MRX50; SYN1; SYN1a; SYN1b; Synapsin; Synapsin I; synapsin Ib; Synapsin-1; SYNI

Synonyms

Brain protein 4.1; MRX50; SYN1; SYN1a; SYN1b; Synapsin; Synapsin I; synapsin Ib; Synapsin-1; SYNI

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