Synaptophysin Rabbit mAb,ABclonal,A27659

Reactivity

Human, Mouse, Rat

Application

WB, IP, IF-F, IF-P, IHC-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB594571464

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameSynaptophysin Rabbit mAb
Cat. No.A27659
Accession NumberP08247
Gene ID (Entrez)6855
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IP, IF-F, IF-P, IHC-P, ELISA
Working DilutionsWB:1:5000 - 1:40000 | IP:0.5μg-4μg antibody for 500μg-700μg extracts of whole cells | IF-F:1:200 - 1:800 | IF-P:1:200 - 1:800 | IHC-P:1:500 - 1:2000 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC74719
Molecular Weight38 kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Regulatory StatusResearch Use Only

Scientific Background

Synaptophysin (SYP, also known as major synaptic vesicle protein p38) is a 38-kDa integral membrane glycoprotein that regulates synaptic vesicle endocytosis. It is the most abundant synaptic vesicle protein by mass. Synaptophysin is present in neuroendocrine cells and neurons that participate in synaptic transmission. Synaptophysin is a useful marker for the identification of neuroendocrine cells and neoplasms. Synaptic proteins including synaptophysin are reduced in brain tissue from patients with Alzheimer's disease.(PMID: 3010302; 21658579)

Synonyms

SYP; SYN; MRX96

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