TANK antibody,Genetex,GTX14272

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB913942001

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTANK antibody
Cat. No.GTX14272
Gene ID (Entrez)10010
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetTANK
ImmunogenImmunogen Sequence: GI # 19743571, sequence 1-110 Recombinant TRAF interacting protein TANK isoform b
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The TRAF (tumor necrosis factor receptor associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, this protein can block TRAF2 binding to LMP1, the Epstein Barr virus transforming protein, and inhibit LMP1-mediated NF kappa B activation.

Synonyms

TRAF family member associated NFKB activator , I-TRAF , ITRAF , TRAF2

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.