TCF12 antibody,Genetex,GTX84997

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB ICC/IF ELISA

Conjugate

Unconjugated

Platform ID

BAB322690765

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTCF12 antibody
Cat. No.GTX84997
Gene ID (Entrez)6938
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTCF12
ImmunogenTCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12.The immunogen is located within amino acids 50 - 100 of TCF12.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.

Synonyms

transcription factor 12 , CRS3 , HEB , HTF4 , HsT17266 , TCF-12 , bHLHb20 , p64

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.