TGF beta Receptor III antibody [5G9],Genetex,GTX52508

Host

Mouse

Reactivity

Human

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB871239979

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTGF beta Receptor III antibody [5G9]
Cat. No.GTX52508
Gene ID (Entrez)7049
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityMonoclonal
Concentration200 μg/ml (Please refer to the vial label for the specific concentration.)
TargetTGFBR3
ImmunogenRecombinant huTGFβRIII extra cellular domain
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

Synonyms

BGCAN , TGFBR3 , betaglycan , transforming growth factor beta receptor 3 , TGF beta Receptor III , TGF beta receptor 3

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