TGF beta Receptor antibody,Genetex,GTX17282

Host

Sheep

Reactivity

Bird

Application

WB IHC

Conjugate

Unconjugated

Platform ID

BAB294526819

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTGF beta Receptor antibody
Cat. No.GTX17282
HostSheep
IsotypeIgG
ReactivityBird
ConjugationUnconjugated
ApplicationWB IHC
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenGST fusion avian protein, containing chick transforming growth factor b type II receptor (aa 77 - 148).
PurityImmunogen affinity purified
Appearance/FormLiquid
FormulationPBS,0.08% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Three members of the TGF beta family, TGF beta 1, TGF beta 2 and TGF beta 3, are known in mammals. TGF betas mediate their activity by high affinity binding to the type 2 receptor, which requires both its kinase activity and association with members of a series of related type 1 receptors called activin receptor-like kinase (ALK) 1 to 6. Of these, only ALK5 has been shown to represent a functional TGF beta type 1 receptor, but only ALK2 and ALK4 bind activin with high affinity. TGF beta R3 binds TGF beta and retains TGF beta for presentation to the signaling receptors.

Synonyms

Transforming growth factor beta receptor II (70-80kDa) , TGF beta receptor , Transforming growth factor beta receptor II , TGF beta receptor type II precursor , TGF beta type II receptor , Transforming growth factor beta receptor II (7080kDa) , TGFR2

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