TGF beta antibody [TB21],Genetex,GTX76527

Host

Mouse

Reactivity

Human, Mouse, Rat, Rabbit, Sheep, Bovine, Mink, Mustelid

Application

WB IHC-P IHC-Fr FCM ELISA

Conjugate

Unconjugated

Platform ID

BAB490643902

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTGF beta antibody [TB21]
Cat. No.GTX76527
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse, Rat, Rabbit, Sheep, Bovine, Mink, Mustelid
ConjugationUnconjugated
ApplicationWB IHC-P IHC-Fr FCM ELISA
ClonalityMonoclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenHuman Transforming Growth Factor Beta 1 from platelets.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]

Synonyms

LAP Antibody , CED Antibody , TGFB1 Antibody , transforming growth factor, beta 1 Antibody , TGFB Antibody , DPD1 Antibody , TGFbeta Antibody

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