TGF beta antibody [TB21],Genetex,GTX76527
Host
Mouse
Reactivity
Human, Mouse, Rat, Rabbit, Sheep, Bovine, Mink, Mustelid
Application
WB IHC-P IHC-Fr FCM ELISA
Conjugate
Unconjugated
Platform ID
BAB490643902
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Specifications
Scientific Background
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009]
Synonyms
LAP Antibody , CED Antibody , TGFB1 Antibody , transforming growth factor, beta 1 Antibody , TGFB Antibody , DPD1 Antibody , TGFbeta Antibody
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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