THAP1 Antibody (YA4530)(PBS only),MedChemexpress,HY-P84833A

THAP1 Antibody (YA4530) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to THAP1.

Host

Mouse

Reactivity

Human

Application

ICC/IF,FC,ELISA

Conjugate

Non-conjugated

Platform ID

BAB890812190

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTHAP1 Antibody (YA4530)(PBS only)
Cat. No.HY-P84833A
Accession NumberQ9NVV9
Gene ID (Entrez)55145
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationNon-conjugated
ApplicationICC/IF,FC,ELISA
Working DilutionsICC/IF: 1:200-1:1000; FC: 1:200-1:400; ELISA: 1:10000
Clone NumberYA4530
Molecular WeightPredicted band size: 24.9 kDa; Observed band size: 25-30 kDa
ImmunogenPurified recombinant fragment of human THAP1 (AA: 1-213) expressed in E. Coli.
Purityaffinity purified.
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, pH 7.4.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

THAP1 is a DNA-binding transcription regulator that controls endothelial cell proliferation and G1/S cell-cycle progression. It specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and modulates the expression of pRB-E2F cell-cycle target genes, including RRM1. As part of the THAP1/THAP3-HCFC1-OGT complex, it is essential for regulating RRM1 transcriptional activity. Additionally, THAP1 may exhibit pro-apoptotic activity by enhancing both serum-withdrawal and TNF-induced apoptosis.

Synonyms

DYT6

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