TIMP2 Antibody (YA3262),MedChemexpress,HY-P83517

TIMP2 Antibody (YA3262) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TIMP2.

Host

Rabbit

Reactivity

Human

Application

WB,FC

Conjugate

Non-conjugated

Platform ID

BAB832939982

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

1 Deer Park Drive, Suite FMONMOUTH JUNCTION, NI 08852, USA

Contact

Tel: 609-228-6898
Fax: 609-228-5909

Product Specifications
Scientific Background
Synonyms

Specifications

NameTIMP2 Antibody (YA3262)
Cat. No.HY-P83517
Accession NumberP16035
Gene ID (Entrez)7077
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,FC
Working DilutionsWB: 1:500-1:1000; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA3262
Molecular WeightPredicted band size: 24 kDa; Observed band size: 24 kDa
ImmunogenA synthesized peptide derived from human TIMP2 aa170-220/220.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The related gene is a member of the TIMP related gene family. The proteins encoded by The related gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Synonyms

CSC21K; TIMP 2; TIMP2

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