TLR4 antibody [MTS510],Genetex,GTX29104

Host

Rat

Reactivity

Mouse

Application

FCM IP Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB184357197

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTLR4 antibody [MTS510]
Cat. No.GTX29104
Gene ID (Entrez)21898
HostRat
IsotypeIgG2a
ReactivityMouse
ConjugationUnconjugated
ApplicationFCM IP Neutralizing /Inhibition
ClonalityMonoclonal
Concentration0.5 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTlr4
ImmunogenThis antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (Akashi et al, 2000).
PurityProtein G purified
Appearance/FormLiquid
FormulationPBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Synonyms

toll-like receptor 4 , Lps , Ly87 , Ran/M1 , Rasl2-8

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