TLR6 antibody [TLR6.127],Genetex,GTX54477

Host

Mouse

Reactivity

Human

Application

ICC/IF IHC-P FCM IP Functional Assay

Conjugate

Unconjugated

Platform ID

BAB504948297

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTLR6 antibody [TLR6.127]
Cat. No.GTX54477
Gene ID (Entrez)10333
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF IHC-P FCM IP Functional Assay
ClonalityMonoclonal
Concentration100 μg/ml (Please refer to the vial label for the specific concentration.)
TargetTLR6
PurityPurified IgG1
Appearance/FormLiquid
FormulationFilter-sterilized PBS, 0.1% BSA,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.[provided by RefSeq, Jan 2011]

Synonyms

CD286,TLR6,toll like receptor 6

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