TLR7 Recombinant Antibody,Bioss,bsm-41320r-100ul

Host

Rabbit

Reactivity

Human

Application

WB, FCM

Conjugate

Unconjugated

Platform ID

BAB474760035

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameTLR7 Recombinant Antibody
Cat. No.bsm-41320r-100ul
Accession NumberQ9NYK1
Gene ID (Entrez)51284
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, FCM
Working DilutionsWB:1:500-2000 | FCM:FCM1ug/Test
ClonalityRecombinant
Concentration1ug/ul
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Synonyms

TLR-7; PRO285; TLR 7; TLR7_HUMAN; Toll like receptor 7; Toll-like receptor 7; UNQ248.

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