TLR9 antibody,Genetex,GTX31244

Host

Goat

Reactivity

Human, Mouse

Application

WB IHC-P

Conjugate

Unconjugated

Platform ID

BAB061793527

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTLR9 antibody
Cat. No.GTX31244
Gene ID (Entrez)54106
HostGoat
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IHC-P
ClonalityPolyclonal
Concentration1.0 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTLR9
ImmunogenSynthetic peptide SLKYNNLTVVPRNLPSSLEYLLLSYNRIVKL corresponding to amino acids 205-235 within the N-terminal domain of human TLR9
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.1% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]

Synonyms

toll like receptor 9 , CD289

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