TLS/FUS Antibody (YA3197),MedChemexpress,HY-P83452

TLS/FUS Antibody (YA3197) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TLS/FUS.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,FC

Conjugate

Non-conjugated

Platform ID

BAB520033927

Suppliers

(1)

Biomedical Life sciences

91-9676853503

[email protected]
Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

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Product Specifications
Verification Image
Scientific Background
Synonyms

Specifications

NameTLS/FUS Antibody (YA3197)
Cat. No.HY-P83452
Accession NumberP35637
Gene ID (Entrez)2521
HostRabbit
RRIDAB_3105563
IsotypeIgG
SensitivityEndogenous
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,FC
Working DilutionsWB: 1:500-1:1000; IHC-P: 1:50-1:100; ICC/IF: 1:50-1:200; FC: 1:50-1:100
ClonalityRecombinant,Monoclonal
Clone NumberYA3197
Molecular WeightPredicted band size: 53 kDa; Observed band size: 70 kDa
ImmunogenA synthesized peptide derived from human FUS / TLS aa1-31.
PurityAffinity Chromatography
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Verification Image

Scientific Background

The related gene encodes a multifunctional protein component of the heterorelated geneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. The protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of related gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in The related gene result in amyotrophic lateral sclerosis type 6.

Synonyms

FUS; FUS-CHOP; TLS; 75 kDa DNA-pairing protein; Oncogene FUS; Oncogene TLS; POMP75; Translocated in liposarcoma protein

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