TMP21 antibody,Genetex,GTX85770

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IHC-P ELISA

Conjugate

Unconjugated

Platform ID

BAB513333006

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTMP21 antibody
Cat. No.GTX85770
Gene ID (Entrez)10972
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P ELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTMED10
ImmunogenA 19 amino acid synthetic peptide near the C-terminus of human TMP21. The immunogen is located within amino acids 160 - 210 of TMP21.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]

Synonyms

transmembrane p24 trafficking protein 10 , P24(DELTA) , S31I125 , S31III125 , TMED10 , TMP21 , Tmp21I , p23 , p24d1

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