TNFR1 Polyclonal Antibody,Bioss,bs-22306r

Host

Rabbit

Reactivity

Human

Application

WB, IHC-P, IHC-F, IF

Conjugate

Unconjugated

Platform ID

BAB551145881

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTNFR1 Polyclonal Antibody
Cat. No.bs-22306r
Accession NumberP19438
Gene ID (Entrez)7132
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IHC-P, IHC-F, IF
Working DilutionsWB:=1:500-2000 | IHC-P:IHC-P=1:100-500 | IHC-F:IHC-F=1:100-500 | IF:IF=1:100-500
ClonalityPolyclonal
Concentration1mg/ml
PurityPurified by Protein A.
Formulation0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageShipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

Synonyms

TNFRSF1a; CD120a; CD120a antigen; MGC19588; p55; p55 R; p55R; p60; TBP1; TBPI; TNF R; TNF R I; TNF R1; TNF R55; TNF-R1; Soluble TNF Receptor I; Soluble TNF p55 Receptor; TNF-RI; TNFR 1; TNFR I; TNFR-I; TNFR55; TNFR60; TNFRI; TNFRSF1a; TNR1A_HUMAN; Tumor necrosis factor alpha receptor; Tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; Tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; Tumor necrosis factor-binding protein 1.

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