TNFRSF10A Rabbit pAb- ABclonal,ABclonal,A12540

Reactivity

Human, Mouse, Rat

Application

WB, IF/ICC, IF-P, ELISA

Conjugate

Unconjugated

Platform ID

BAB246071238

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTNFRSF10A Rabbit pAb- ABclonal
Cat. No.A12540
Accession NumberO00220
Gene ID (Entrez)8797
RRIDAB_2759380
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IF/ICC, IF-P, ELISA
Working DilutionsWB:1:500 - 1:2000 | IF/ICC:1:50 - 1:100 | IF-P:1:50 - 1:100 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight40-55kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.

Synonyms

DR4; APO2; CD261; TRAILR1; TRAILR-1; TNFRSF10A

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