TRAP1/HSP75 Recombinant Antibody,Bioss,bsm-62997r

Host

Rabbit

Reactivity

Human

Application

WB, IP

Conjugate

Unconjugated

Platform ID

BAB202234588

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Product Specifications
Scientific Background
Synonyms

Specifications

NameTRAP1/HSP75 Recombinant Antibody
Cat. No.bsm-62997r
Accession NumberQ12931
Gene ID (Entrez)10131
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB, IP
Working DilutionsWB:1:300-5000 | IP:1-2ug
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Synonyms

HSP75; HSP 75; HSP90L; TRAP-1.

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