TRIM3 antibody, N-term,Genetex,GTX89826

Host

Goat

Reactivity

Human, Mouse, Rat

Application

WB

Conjugate

Unconjugated

Platform ID

BAB151339260

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTRIM3 antibody, N-term
Cat. No.GTX89826
Gene ID (Entrez)10612
HostGoat
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTRIM3
ImmunogenPeptide with sequence AKREDSPGPEVQP-C, from the N Terminus of the protein sequence according to NP_006449.2; NP_150594.2.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the 'RING-B-box-coiled-coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4. Thus it is suggested that this human protein may play a role in myosin V-mediated cargo transport. Alternatively spliced transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]

Synonyms

tripartite motif containing 3 , BERP , HAC1 , RNF22 , RNF97

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