TSC2 Rabbit pAb- ABclonal,ABclonal,A0492
Reactivity
Human, Mouse, Rat
Application
WB, IHC-P, IF/ICC, ELISA
Conjugate
Unconjugated
Platform ID
BAB184289643
ABclonal
Contact
Tel:
Fax:
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameTSC2 Rabbit pAb- ABclonal
Cat. No.A0492
Accession NumberP49815
Gene ID (Entrez)7249
RRIDAB_2757221
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB, IHC-P, IF/ICC, ELISA
Working DilutionsWB:1:500 - 1:1000 | IHC-P:1:50 - 1:200 | IF/ICC:1:50 - 1:200 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Molecular Weight200kDa
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only
Scientific Background
This gene is a tumor suppressor gene that encodes the growth inhibitory protein tuberin. Tuberin interacts with hamartin to form the TSC protein complex which functions in the control of cell growth. This TSC protein complex negatively regulates mammalian target of rapamycin complex 1 (mTORC1) signaling which is a major regulator of anabolic cell growth. Mutations in this gene have been associated with tuberous sclerosis and lymphangioleiomyomatosis.
Synonyms
LAM; TSC4; PPP1R160; TSC2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.