TSG101 Recombinant Antibody, AbBy Fluor-680 Conjugated,Bioss,bsm-52746r-bf680-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB, FCM, IF(IHC-P), IF(ICC)

Conjugate

AbBy Fluor-680

Platform ID

BAB592625961

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTSG101 Recombinant Antibody, AbBy Fluor-680 Conjugated
Cat. No.bsm-52746r-bf680-100ul
Accession NumberQ99816
Gene ID (Entrez)7251
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationAbBy Fluor-680
ApplicationWB, FCM, IF(IHC-P), IF(ICC)
Working DilutionsWB:1:500-2000 | FCM:FCM1:50-100 | IF(IHC-P):IFIHC-P1:50-200 | IF(ICC):IFICC1:50-200
ClonalityMonoclonal
ConcentrationLot dependent
PurityPurified by Protein A.
FormulationAqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
StorageStore at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Scientific Background

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

Synonyms

Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101

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