TXA synthase antibody [2C1],Genetex,GTX83523

Host

Mouse

Reactivity

Human, Rat

Application

WB ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB881024016

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameTXA synthase antibody [2C1]
Cat. No.GTX83523
Gene ID (Entrez)6916
HostMouse
IsotypeIgG2a
ReactivityHuman, Rat
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM
ClonalityMonoclonal
Concentration0.86 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTBXAS1
ImmunogenFull length human recombinant protein of human TBXAS1(NP_001052) produced in HEK293T cell.
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Synonyms

thromboxane A synthase 1 , BDPLT14 , CYP5 , CYP5A1 , GHOSAL , THAS , TS , TXAS , TXS

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