TYK2 antibody [N1N2], N-term,Genetex,GTX111445

Host

Rabbit

Reactivity

Human

Application

ICC/IF

Conjugate

Unconjugated

Platform ID

BAB377109689

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameTYK2 antibody [N1N2], N-term
Cat. No.GTX111445
Gene ID (Entrez)7297
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationICC/IF
ClonalityPolyclonal
Concentration0.7 mg/ml (Please refer to the vial label for the specific concentration.)
TargetTYK2
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human TYK2. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 20% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]

Synonyms

tyrosine kinase 2 , IMD35 , JTK1

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