Thrombomodulin antibody [15C8],Genetex,GTX01950

Host

Mouse

Reactivity

Human

Application

IHC-P

Conjugate

Unconjugated

Platform ID

BAB343825673

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameThrombomodulin antibody [15C8]
Cat. No.GTX01950
Gene ID (Entrez)7056
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P
ClonalityMonoclonal
TargetTHBD
ImmunogenProkaryotic recombinant protein corresponding to the epidermal growth factor homology domain of the human CD141 molecule.
PurityUnpurified
Appearance/FormLiquid
FormulationTissue culture supernatant,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]

Synonyms

thrombomodulin , AHUS6 , BDCA3 , CD141 , THPH12 , THRM , TM

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