Tissue Factor Pathway Inhibitor Antibody (YA3272),MedChemexpress,HY-P83527

Tissue Factor Pathway Inhibitor Antibody (YA3272) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tissue Factor Pathway Inhibitor.

Host

Rabbit

Reactivity

Human

Application

WB,IP

Conjugate

Non-conjugated

Platform ID

BAB958002452

Suppliers

(1)

Biomedical Life sciences

91-9676853503

Country:India
City:Madīnat Ḩamad
Plot No.A-2811121/A&B/3.IP NACHARAM. ALA NACHARAM, Road N0-15, Hyderabad Medchal Malkajgiri, Telangana-500076
Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

Headquarters

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Contact

Tel: 609-228-6898
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Product Specifications
Scientific Background
Synonyms

Specifications

NameTissue Factor Pathway Inhibitor Antibody (YA3272)
Cat. No.HY-P83527
Accession NumberP10646
Gene ID (Entrez)7035
HostRabbit
IsotypeIgG
SensitivityEndogenous
ReactivityHuman
ConjugationNon-conjugated
ApplicationWB,IP
Working DilutionsWB: 1:500-1:1000; IP: 1:20
ClonalityRecombinant,Monoclonal
Clone NumberYA3272
Molecular WeightPredicted band size: 35 kDa; Observed band size: 40-55 kDa
ImmunogenRecombinant protein of human TFPI
PurityAffinity Purified
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The related gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of The related gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. The related gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization.

Synonyms

EPI; TFI; LACI; TFPI1

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