Tollip antibody [Kimmy-2],Genetex,GTX16089
Host
Mouse
Reactivity
Human, Mouse
Application
WB IP
Conjugate
Unconjugated
Platform ID
BAB541353343
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameTollip antibody [Kimmy-2]
Cat. No.GTX16089
Gene ID (Entrez)54473
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB IP
ClonalityMonoclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetTollip
ImmunogenTollip (monoclonal Kimmy-2) antibody was raised against recombinant mouse Tollip (aa. 1-274).
PurityPurified IgG1
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Regulatory StatusResearch Use Only
Scientific Background
Toll like protein is a component of the signaling pathway of IL-1 and Toll-like receptors. It inhibits cell activation by microbial products. Tollip recruits IRAK1 to the IL-1 receptor complex and inhibits IRAK1 phosphorylation and kinase activity. It oligomerizes and binds to TLR2 and the TLR4-MD2 complex via its C-terminus.
Synonyms
toll interacting protein , 4930403G24Rik , 4931428G15Rik
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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