TotalSeq-A0060 anti-human CD90 Thy1 Antibody anti-CD90 - 5E10,BioLegend,328135

Clone 5E10 recognizes an epitope on Thy-1 independent of its glycosylation, but is abolished under reducing conditions.4Additional reported (for the relevant formats) applications include: immunohistochemical staining of acetone-fixed frozen sections, immunoprecipitation1, and immunofluorescence3.

Host

Mouse

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB129438513

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Product Specifications
Scientific Background

Specifications

NameTotalSeq-A0060 anti-human CD90 Thy1 Antibody anti-CD90 - 5E10
Cat. No.328135
HostMouse
RRIDAB_2734312 (BioLegend Cat. No. 328135)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number50000000000
Concentration0.5 mg/ml
TargetCD90
ImmunogenHEL cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.

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