TotalSeq-A0153 anti-human KLRG1 MAFA Antibody, KLRG1, SA231A2,BioLegend,367721
Host
Mouse
Reactivity
Human
Application
PG -Quality tested
Platform ID
BAB826405188
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
Email:
Product Specifications
Scientific Background
Specifications
NameTotalSeq-A0153 anti-human KLRG1 MAFA Antibody, KLRG1, SA231A2
Cat. No.367721
HostMouse
RRIDAB_2750373 (BioLegend Cat. No. 367721)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberSA231A2
Concentration0.5 mg/ml
TargetKLRG1
ImmunogenHuman KLRG1-transfected cells
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.