TotalSeq-A0575 anti-human CD49a Antibody, CD49a, TS2/7,BioLegend,328315
Additional reported applications include: immunoprecipitation1, immunohistochemical staining1of acetone-fixed frozen tissue sections, and spatial biology (IBEX)3,4.
Host
Mouse
Reactivity
Human
Application
PG -Quality tested
Platform ID
BAB533900600
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq-A0575 anti-human CD49a Antibody, CD49a, TS2/7
Cat. No.328315
HostMouse
RRIDAB_2783195 (BioLegend Cat. No. 328315)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberTS2/7
Concentration0.5 mg/ml
TargetCD49a
ImmunogenHuman CTL line
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD49a is a 200 kD type I transmembrane glycoprotein also known as α1integrin, VLA-1 α chain, or Integrin α1. It associates with CD29 (β1integrin) to form VLA-1 complex, a collagen IV and alminin-1 receptor. It is expressed on activated T cells, monocytes, NK cells, smooth muscle cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is an adhesion molecule and is involved in the regulation of leukocyte migration, T cell proliferation, and cytokine production.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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