TotalSeq-A0807 anti-mouse CD200R OX2R Antibody, CD200R, OX-110,BioLegend,123913

Additional applications (for the relevant formats) include:in vivostudies3. The Ultra-LEAF™ purified antibody is recommended for functional assays.

Host

Rat

Reactivity

Mouse

Application

PG -Quality tested

Platform ID

BAB450029613

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq-A0807 anti-mouse CD200R OX2R Antibody, CD200R, OX-110
Cat. No.123913
HostRat
RRIDAB_2800594 (BioLegend Cat. No. 123913)
IsotypeRat IgG2a, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberOX-110
Concentration0.5 mg/ml
TargetCD200R
ImmunogenFusion protein mouse CD200RCD4d3
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD200R, also known as OX2R, is a membrane glycoprotein with up to 70% of its weight derived from N-linked glycosylation. CD200R is expressed primarily by monocytes and neutrophils but also by other leukocytes including T lymphocytes and mast cells. The interaction between CD200 and CD200R may contribute to pathways that suppress and limit macrophage induced inflammatory damage in tissue. Studies suggest that CD200-CD200R interaction may be involved in the control of myeloid cellular function. Levels of expression on resting peripheral blood cells are relatively low.

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