TotalSeq™-A0872 anti-human CD84 Antibody, CD84, CD84.1.21,BioLegend,326011

Additional reported (for the relevant formats) applications include: immunoprecipitation2, and enhancing CD3 induced IFN-? production1 and partially block CD84-Ig binding to lymphocytes1.

Host

Mouse

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB653576921

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-A0872 anti-human CD84 Antibody, CD84, CD84.1.21
Cat. No.326011
HostMouse
RRIDAB_2814189 (BioLegend Cat. No. 326011)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberCD84.1.21
Concentration0.5 mg/ml
TargetCD84
Immunogen300.19 cell line transfected with the CD84 full-length DNA
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of (preferentially on CD45RO+) T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. The antibody CD84.1.21 is able to enhance CD3 induced IFN-γ production and partially block CD84-Ig binding to lymphocytes.

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