TotalSeq™-A1033 anti-mouse IL-23R Antibody, IL-23R, 12B2B64,BioLegend,150909
Host
Rat
Reactivity
Mouse
Application
PG -Quality tested
Platform ID
BAB417134146
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-A1033 anti-mouse IL-23R Antibody, IL-23R, 12B2B64
Cat. No.150909
HostRat
RRIDAB_2860717 (BioLegend Cat. No. 150909)
IsotypeRat IgG2b, κ
ReactivityMouse
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number12B2B64
Concentration0.5 mg/mL
TargetIL-23R
ImmunogenPartial mouse IL-23R recombinant protein (aa 24-374)
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
IL-23R is a 72 kD protein that associates with IL-12RB1 to form a heterodimer. It is a ligand for IL-23 and stimulates T, NK and some myeloid cells. It is necessary for generation of Th17 cells but is not required for maintenance of previously generated Th17 cells. Expression of IL-23R or mutations in the IL23R gene has been associated with autoimmunity and may also be important in tumor biology.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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