TotalSeq™-A1292 anti-human CD179b (Ig λ5) Antibody, CD179b, HSL11,BioLegend,349805
Additional reported applications (for the relevant formats) include: immunoprecipitation1and immunohistochemistry of frozen and paraffin-embedded samples2.
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB174816721
BioLegend
Contact
Tel: 1-858-455-9588
Fax: +49 (4131) 7023913
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-A1292 anti-human CD179b (Ig λ5) Antibody, CD179b, HSL11
Cat. No.349805
HostMouse
RRIDAB_3106265 (BioLegend Cat. No. 349805)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberHSL11
Concentration0.5 mg/mL
TargetCD179b
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
CD179b, also known as Ig Lambda 5, λ5, and Ig omega, is a 22 kD, C-like protein member within the Ig superfamily. λ5 associates with CD179a (VpreB) to form a surrogate light (SL) chain that in turn associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that the deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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