TotalSeq™-A1298 anti-human GPR15 Antibody, GPR15, SA302A10,BioLegend,373021
Host
Mouse
Reactivity
Human
Application
PG - Quality tested
Platform ID
BAB014348725
BioLegend
Contact
Tel: 1-858-455-9588
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Product Specifications
Scientific Background
Specifications
NameTotalSeq™-A1298 anti-human GPR15 Antibody, GPR15, SA302A10
Cat. No.373021
HostMouse
RRIDAB_3662384 (BioLegend Cat. No. 373021)
IsotypeMouse IgG2a, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberSA302A10
Concentration0.5 mg/mL
TargetGPR15
ImmunogenHuman GPR15-transfected cells.
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only
Scientific Background
GPR15, also known as BOB, is a G-protein coupled receptor with 7 transmembrane regions, that is present on the cell surface as an homotrimer. Its ligand, GPR15L, was recently identified. It acts as receptor for human immunodeficiency virus type 1 and 2. GPR15 is expressed by effector T cells and subsets of memory T cells, and is involved in the recruitment of proinflammatory CD4+T cells responsible of the pathogenesis in colitis. It is upregulated on monocytes and neutrophils in the synovia of patients with RA.
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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