TotalSeq™-A1458 anti-human CD248 (Endosialin) Antibody, CD248, B1/35,BioLegend,379105

Host

Mouse

Reactivity

Human

Application

PG - Quality tested

Platform ID

BAB206612716

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-A1458 anti-human CD248 (Endosialin) Antibody, CD248, B1/35
Cat. No.379105
HostMouse
RRIDAB_3106264 (BioLegend Cat. No. 379105)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberB1/35
Concentration0.5 mg/mL
TargetCD248
ImmunogenDiploid human fibroblasts
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

Endosialin, also known as Tumor Endothelial Marker 1 (TEM1), CD248 and CD164 sialomucin-like 1 (CD164L1), is classified as a C-type lectin-like protein and shares both sequence and structural 39% homology with thrombomodulin (CD141) and 33% homology to complement receptor C1qRp (CD93). CD248 is expressed on pericytes and fibroblasts during tissue development, tumor neovascularization and inflammation.

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