TotalSeq™-B0164 anti-human CD1d Antibody, CD1d, 51.1,BioLegend,350323

Additional reported application (for the relevant formats) include: immunohistochemical staining of frozen tissue sections1, Western blotting1,2, and induction of IL-12 production by crosslinking of CD1d3.

Host

Mouse

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB625990169

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0164 anti-human CD1d Antibody, CD1d, 51.1
Cat. No.350323
HostMouse
RRIDAB_2832682 (BioLegend Cat. No. 350323)
IsotypeMouse IgG2b, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone Number51.1
Concentration0.5 mg/mL
TargetCD1d
ImmunogenHuman CD1d-Fc fusion
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
Regulatory StatusResearch Use Only

Scientific Background

CD1d is a MHC-like, type I transmembrane protein, member of the CD1 family and the immunoglobulin superfamily. On the cell surface, CD1d forms a heterodimer with β2-microglobulin. CD1d is expressed by antigen-presenting cells such as B cells, monocytes/macrophages, dendritic cells, and some non-lymphoid cells. Cortical thymocytes express CD1d but the expression is lost in mature T cells. CD1d presents lipid antigens toiNKT cells analogous to MHC molecule presentation of peptides to T cells.

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