TotalSeq™-B0187 anti-human CD79b (Igβ) Antibody, CD79b, CB3-1,BioLegend,341419

Host

Mouse

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB277190087

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0187 anti-human CD79b (Igβ) Antibody, CD79b, CB3-1
Cat. No.341419
HostMouse
RRIDAB_2832667 (BioLegend Cat. No. 341419)
IsotypeMouse IgG1, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberCB3-1
Concentration0.5 mg/mL
TargetCD79b
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD79 is a heterodimeric molecule comprised of an α-chain (CD79a) and β-chain (CD79b). A 37-39 kD type I integral membrane protein CD79b is non-covalently associated with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b is expressed on the surface of surface Ig (sIg)-positive B cells and in the cytoplasm of sIg-negative B cells. It is essential for signal transduction after surface Ig crosslinking.

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