TotalSeq™-B0208 anti-human XCR1 Antibody, XCR1, S15046E,BioLegend,372615

Host

Rat

Reactivity

Human

Application

PG -Quality tested

Platform ID

BAB753528921

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

Email:

Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0208 anti-human XCR1 Antibody, XCR1, S15046E
Cat. No.372615
HostRat
RRIDAB_2814334 (BioLegend Cat. No. 372615)
IsotypeRat IgG2a, κ
ReactivityHuman
ApplicationPG -Quality tested
ClonalityMonoclonal
Clone NumberS15046E
Concentration0.5 mg/ml
TargetXCR1
ImmunogenHuman XCR1-transfected cells.
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

XCR1, also known as GPR5 or CCXCR1, is a 38 kD G-protein coupled, seven transmembrane receptor. It is the only member of the "C" chemokine receptor family and mediates chemotaxis of XCL1 and XCL2 (lymphotactin-1 and -2). XCR1 is expressed on a subset of CD141+conventional dendritic cells. XCR1 is also involved in the migration and proliferation of some cancer cells.

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