TotalSeq™-B0229 anti-mouse/rat CD62P (P-selectin) Antibody, CD62P (P-selectin), RMP-1,BioLegend,148311

Additional reported applications (for the relevant formats) include: immunofluorescence6, immunohistochemistry5, ELISA7, Western blotting4, immunoprecipitation4, and blocking in rats1,2and mice3.

Host

Mouse

Reactivity

Mouse, Rat

Application

PG - Quality tested

Platform ID

BAB523705496

BioLegend

Headquarters

8999 BioLegend Way San Diego, CA 92121 United States

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Contact

Tel: 1-858-455-9588
Fax: +49 (4131) 7023913

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Product Specifications
Scientific Background

Specifications

NameTotalSeq™-B0229 anti-mouse/rat CD62P (P-selectin) Antibody, CD62P (P-selectin), RMP-1
Cat. No.148311
HostMouse
RRIDAB_2892301 (BioLegend Cat. No. 148311)
IsotypeMouse IgG2a, κ
ReactivityMouse, Rat
ApplicationPG - Quality tested
ClonalityMonoclonal
Clone NumberRMP-1
Concentration0.5 mg/mL
TargetCD62P
ImmunogenThrombin activated rat platelets
PurityThe antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer under optimal conditions.
FormulationPhosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and EDTA
StorageThe antibody solution should be stored undiluted between 2°C and 8°C.Do not freeze.
Regulatory StatusResearch Use Only

Scientific Background

CD62P is a 140 kD type I transmembrane glycoprotein, also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62P is primarily stored in secretory α-granules in platelets and Weibel-Palade bodies in endothelial cells, and is rapidly relocated to the plasma membrane upon activation. The ligands for CD62P are CD162 and CD24. A primary function of CD62P is cell adhesion during neutrophil rolling, and platelet-neutrophil and platelet-monocyte interactions.

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